TEC01-Práctica segura en el uso de medicamentos

Comprehensive physicochemical characterization of a peptide-based medicine: Teduglutide (Revestive®) structural description and stress testing

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023;

FI:4,9; Q1

Analysing the In-Use Stability of mRNA-LNP COVID-19 Vaccines Comirnaty™ (Pfizer) and Spikevax™ (Moderna): A Comparative Study of the Particulate

VACCINES, 2023;

FI:7,8; Q1

Azathioprine dose tailoring based on pharmacogenetic information: Insights of clinical implementation

BIOMEDICINE & PHARMACOTHERAPY, 2023;

FI:7,5; Q1

QbD/PAT-State of the Art of Multivariate Methodologies in Food and Food-Related Biotech Industries

FOOD ENGINEERING REVIEWS, 2023;

FI:6,6; Q1

Gut Microbiota Composition Can Predict Colonization by Multidrug-Resistant Bacteria in SARS-CoV-2 Patients in Intensive Care Unit: A Pilot Study

ANTIBIOTICS-BASEL, 2023;

FI:4,8; Q2

Applications of multivariate data analysis in shelf life studies of edible vegetal oils – A review of the few past years

FOOD PACKAGING AND SHELF LIFE, 2022;

FI:8,749; D1

Innovative and thorough practice to certify reference materials for sensory defects of olive oil

FOOD CHEMISTRY, 2022;

FI:9,231; D1

Pharmacogenetics of siponimod: A systematic review

BIOMEDICINE & PHARMACOTHERAPY, 2022;

FI:7,419; D1

Public healthcare costs associated with long-term exposure to mixtures of persistent organic pollutants in two areas of Southern Spain: A longitudinal analysis

ENVIRONMENTAL RESEARCH, 2022;

FI:8,431; D1

Combined use of UV and MS data for ICH Stability-Indication Method: Quantification and isoforms identification of intact nivolumab

MICROCHEMICAL JOURNAL, 2022;

FI:5,304; Q1

Chromatographic fingerprinting by comprehensive two-dimensional chromatography: Fundamentals and tools

TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2021;

FI:12,296; D1

Associations of residential and occupational history with the distribution of persistent pollutant mixtures in adipose tissue samples.-

ENVIRONMENTAL RESEARCH, 2021;

FI:6,498; D1

Chromatographic Fingerprinting Enables Effective Discrimination and Identitation of High-Quality Italian Extra-Virgin Olive Oils

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021;

FI:5,279; D1

Data mining/machine learning methods in foodomics

CURRENT OPINION IN FOOD SCIENCE, 2021;

FI:6,031; D1

A Sensor-Based Methodology to Differentiate Pure and Mixed White Tequilas Based on Fused Infrared Spectra and Multivariate Data Treatment

CHEMOSENSORS, 2021;

FI:3,398; Q2

A perfect tandem: chemometric methods and microfluidic colorimetric twin sensors on paper. Beyond the traditional analytical approach

MICROCHEMICAL JOURNAL, 2020;

FI:3,594; Q1

Authentication of the geographical origin and the botanical variety of avocados using liquid chromatography fingerprinting and deep learning methods

CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 2020;

FI:2,895; Q1

Comprehensive biophysical and functional study of ziv-aflibercept: characterization and forced degradation

SCIENTIFIC REPORTS, 2020;

FI:3,998; Q1

Comparing different domains of analysis for the characterisation of N-glycans on monoclonal antibodies

JOURNAL OF PHARMACEUTICAL ANALYSIS, 2020;

FI:2,673; Q3

Dalbavancin is a novel antimicrobial against Gram-positive pathogens: clinical experience beyond labelled indications

EUROPEAN JOURNAL OF HOSPITAL PHARMACY-SCIENCE AND PRACTICE, 2020;

FI:0,892; Q4

Comparative Stability Studies of Different Infliximab and Biosimilar CT-P13 Clinical Solutions by Combined Use of Physicochemical Analytical Techniques and Enzyme-Linked Immunosorbent Assay (ELISA)

BIODRUGS, 2019;

FI:4,903; D1

Impact of single nucleotide polymorphisms on the efficacy and toxicity of EGFR tyrosine kinase inhibitors in advanced non-small cell lung cancer patients

MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH, 2019;

FI:6,081; D1

The Importance of the Microbiome in Critically Ill Patients: Role of Nutrition

NUTRIENTS, 2019;

FI:4,171; Q1

Pharmacogenetics in the Treatment of Cardiovascular Diseases and Its Current Progress Regarding Implementation in the Clinical Routine

GENES, 2019;

FI:3,331; Q2

Cost-effectiveness analysis of pharmacogenomics-guided clopidogrel treatment in Spanish patients undergoing percutaneous coronary intervention

PHARMACOGENOMICS JOURNAL, 2019;

FI:3,503; Q2

Solver, an Excel application to solve the difficulty in applying different univariate linear regression methods

CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 2018;

FI:2,701; D1

Multivariate approaches for stability control of the olive oil reference materials for sensory analysis-part II: applications

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2018;

FI:2,379; Q1

Multivariate approaches for stability control of the olive oil reference materials for sensory analysis-part I: framework and fundamentals

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2018;

FI:2,379; Q1

Validated reverse phase HPLC diode array method for the quantification of intact bevacizumab, infliximab and trastuzumab for long-term stability study

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018;

FI:3,909; Q1

Study of aggregation in therapeutic monoclonal antibodies subjected to stress and long-term stability tests by analyzing size exclusion liquid chromatographic profiles

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018;

FI:3,909; Q1

One input-class and two input-class classifications for differentiating olive oil from other edible vegetable oils by use of the normal-phase liquid chromatography fingerprint of the methyl-transesterified fraction

FOOD CHEMISTRY, 2017;

FI:4,529; D1

Method for the comparison of complex matrix assisted laser desorption ionization-time of flight mass spectra. Stability of therapeutical monoclonal antibodies

CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 2017;

FI:2,303; D1

Pigment-size effect on the physico-chemical behavior of azurite-tempera dosimeters upon natural and accelerated photo aging

DYES AND PIGMENTS, 2017;

FI:3,473; D1

Principal Component Analysis to interpret changes in chromatic parameters on paint dosimeters exposed long-term to urban air

CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 2017;

FI:2,303; D1

Implementing Pharmacogenomics in Europe: Design and Implementation Strategy of the Ubiquitous Pharmacogenomics Consortium

CLINICAL PHARMACOLOGY & THERAPEUTICS, 2017;

FI:7,266; D1

Combined untargeted and targeted fingerprinting with comprehensive two-dimensional chromatography for volatiles and ripening indicators in olive oil

ANALYTICA CHIMICA ACTA, 2016;

FI:4,712; D1

Quality performance metrics in multivariate classification methods for qualitative analysis

TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2016;

FI:7,487; D1

Chromatographic fingerprinting: An innovative approach for food ‘identitation’ and food authentication – A tutorial

ANALYTICA CHIMICA ACTA, 2016;

FI:4,712; D1

Authentication of canned fish packing oils by means of Fourier transform infrared spectroscopy

FOOD CHEMISTRY, 2016;

FI:4,052; D1

Results of genotype-guided antiplatelet therapy in patients who undergone percutaneous coronary intervention with stent

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2016;

FI:4,638; Q1

Triacylglycerols Determination by High-temperature Gas Chromatography in the Analysis of Vegetable Oils and Foods: A Review of the Past 10 Years

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2015;

FI:5,176; D1

Cluster-based comparison of the peptide mass fingerprint obtained by MALDI-TOF mass spectrometry. A case study: long-term stability of rituximab

ANALYST, 2015;

FI:4,107; D1

Seasonal occurrence and distribution of a group of ECs in the water resources of Granada city metropolitan areas (South of Spain): Pollution of raw drinking water

JOURNAL OF HYDROLOGY, 2015;

FI:3,053; D1

Comparative analysis of monoclonal antibody N-glycosylation using stable isotope labelling and UPLC-fluorescence-MS

ANALYST, 2015;

FI:4,107; D1

Quantitative Host Cell Protein Analysis Using Two Dimensional Data Independent LC-MSE

ANALYTICAL CHEMISTRY, 2015;

FI:5,636; D1

Instrumento automatizado para la evaluación del uso y la resistencia a los antimicrobianos (AI-AMS)

Financiador: AGENCIA ESTATAL DE INVESTIGACIÓN

Número de expediente: CPP2022-009977

Tiempo de ejecución: 01/05/2023 - 31/12/2025

IP: MARIA NUÑEZ NUÑEZ

PROA-HUCSC: Desarrollo e integración de una herramienta inteligente de apoyo a los Programas de Optimización del Uso de Antimicrobianos (PROA)

Financiador: FUNDACION ANDALUZA FARMACIA HOSPITALARIA

Número de expediente: FAFH23-001

Tiempo de ejecución: 01/06/2023 - 31/05/2025

IP: MARIA INMACULADA VALLEJO RODRIGUEZ

Desarrollo de estrategias analíticas avanzadas ad-hoc para estudios compresivos de medicamentos biotecnológicos de naturaleza proteica en ámbito hospitalario: estabilidad en jeringas precargadas e impacto de la estabilidad en los programas de telefarmacia

Financiador: UNIVERSIDAD DE GRANADA

Número de expediente: C-EXP-277-UGR23

Tiempo de ejecución: 01/01/2024 - 31/12/2026

IP: ANTONIO SALMERON GARCIA

Estudios de estabilidad en el tiempo de sobrantes de medicamentos biotecnológicos -anticuerpos monoclonales y proteínas de fusión-. Estudios conformacionales comprensivos.

Financiador: INSTITUTO DE SALUD CARLOS III - FEDER

Número de expediente: PI17/00547

Tiempo de ejecución: 01/01/2018 - 31/12/2020

IP: NATALIA AFRICA NAVAS IGLESIAS

UPGX – Making actionable pharmacogenomic data and effective treatment optimization accessible to every European citizen

Financiador: COMISION EUROPEA

Número de expediente: PHC2015-668353

Tiempo de ejecución: 01/01/2016 - 31/12/2020

IP: CRISTINA LUCIA DAVILA FAJARDO

Elaboración de un algoritmo de decisión que valore el riesgo de nuevos eventos cardiovasculares empleando la tecnología NGS para conocer la respuesta a los antiagregantes plaquetarios en pacientes con SCA sometidos a ICP con implantación de stent:

Financiador: FUNDACIÓN PÚBLICA PARA LA INVESTIGACIÓN BIOSANITARIA DE ANDALUCIA ORIENTAL ALEJANDRO OTERO (FIBAO)

Número de expediente: PE-0413-2018

Tiempo de ejecución: 01/01/2019 - 31/12/2022

IP: CRISTINA LUCIA DAVILA FAJARDO

Estudio clínico de seguimiento postcomercialización en pacientes con aneurismas aórticos toracoabdominales tratados con el sistema de endoprótesis cubierta multirrama E-nside TAAA

Financiador: JOTEC GMBH

Tipo de prueba: INV. CLINICA PRODUCTO SANITARIO COM.

Tiempo de ejecución: 28/01/2022 - 30/06/2031

IP: LUIS MIGUEL SALMERON FEBRES

Recogida de datos de la vida real de la endoprótesis con balón expandible GORE® VIABAHN® VBX cuando se utiliza como stent en puente con endoprótesis ramificadas y fenestradas para el tratamiento de aneurismas de aorta que afectan a las arterias renales-mesentéricas

Financiador: W.L GORE & ASSOCIATES, INC

Tipo de prueba: INV. CLINICA PRODUCTO SANITARIO COM.

Tiempo de ejecución: 07/02/2022 - 31/12/2026

IP: LUIS MIGUEL SALMERON FEBRES

Estudio clínico retrospectivo de seguimiento poscomercialización de los injertos vasculares GORE-TEX® y el injerto vascular GORE® PROPATEN® en la arteriopatía periférica, los aneurismas aórticos y los accesos para diálisis.

Financiador: W.L GORE & ASSOCIATES, INC

Tipo de prueba: INV. CLINICA PRODUCTO SANITARIO COM.

Tiempo de ejecución: 08/10/2021 - 31/12/2022

IP: LUIS MIGUEL SALMERON FEBRES

Phase I Open-label, First-in-human Study to Evaluate Feasibility and Safety of Tissue Engineered Veins in Patients With Chronic Venous Insufficiency

Financiador: FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD

Tipo de prueba: ENSAYO CLINICO COMERCIAL

Tiempo de ejecución: 09/09/2021 - 30/12/2023

IP: LUIS MIGUEL SALMERON FEBRES

VenaSeal Spectrum: Global, Post-Market, Prospective, Multi-Center, Randomized Controlled Trial of the VenaSeal™ Closure System vs. Surgical Stripping or Endothermal Ablation (ETA) for the Treatment of Early and Advanced Stage Superficial Venous Disease

Financiador: MEDTRONIC BAKKEN RESEARCH CENTER B.V.

Tipo de prueba: INV. CLINICA PRODUCTO SANITARIO COM.

Tiempo de ejecución: 09/11/2020 - 28/02/2027

IP: LUIS MIGUEL SALMERON FEBRES

Estudio clínico para evaluar la seguridad, la eficacia, la utilización de recursos y los costes asociados al uso del injerto de endoprótesis torácica adaptable GORE® TAG® con sistema ACTIVE CONTROL para pacientes con patologías de la aorta torácica descen

Financiador: ENDOVASCULAR FOUNDATION

Tipo de prueba: INV. CLINICA PRODUCTO SANITARIO INDEP.

Tiempo de ejecución: 06/07/2020 - 30/12/2024

IP: LUIS MIGUEL SALMERON FEBRES

Estudio observacional retrospectivo para caracterizar y evaluar los resultados clinicos de los pacientes que recibieron Benralizumab tras la aprobacion de sus comercializacion en España. (ESTUDIO ORBE II)

Financiador: ASTRAZENECA FARMACEUTICA ESPAÑA S.A.

Tipo de prueba: ESTUDIO POSAUTORIZACION COMERCIAL

Tiempo de ejecución: 03/11/2020 - 30/06/2021

IP: FRANCISCO CASAS MALDONADO

Estudio observacional para evaluar el manejo clinico y la adecuacion de las estrategias terapeuticas utilizadas en pacientes con enfermedad aterosclerotica estable y el uso de los tratamientos recomendados de acuerdo a las guias clinicas. ESTUDIO APALUSA

Financiador: FUNDACION CASA DEL CORAZON

Tipo de prueba: ESTUDIO POSAUTORIZACION INDEPENDIENTE

Tiempo de ejecución: 17/01/2020 - 30/09/2020

IP: LUIS MIGUEL SALMERON FEBRES